Losartan Potassium and Hydrochlorothiazide

Warning

When pregnancy is detected, discontinue losartan potassium and hydrochlorothiazide tablets as soon as possible

Contraindications

• Hypersensitivity to any component of this product
• Anuria
• Coadministration with aliskiren in patients with diabetes

Adverse Reactions

• Dizziness
• Upper respiratory infection
• Cough
• Back pain
• Hyperkalemia
• Hypotension

General Guidance

Dose adjustments may be necessary in patients with renal impairment or hepatic insufficiency

Pregnancy

• Losartan potassium and hydrochlorothiazide can cause fetal harm when administered to a pregnant woman
• Discontinue losartan potassium and hydrochlorothiazide tablets as soon as possible when pregnancy is detected

Nursing Mothers

• It is not known whether losartan is excreted in human milk
• Thiazides appear in human milk
• A decision should be made whether to discontinue nursing or discontinue the drug

Pediatric Use

• Safety and effectiveness of losartan potassium and hydrochlorothiazide in pediatric patients have not been established

Geriatric Use

• In a controlled clinical study, no overall differences in effectiveness were observed between geriatric patients and younger patients
• Adverse events were somewhat more frequent in the elderly compared to non-elderly patients