ARIPIPRAZOLE LAUROXIL
Manufacturer: Alkermes, Inc.
Score: 144.0
ARISTADA INITIO is an atypical antipsychotic used for the initiation of ARISTADA treatment in adults with schizophrenia. It is administered as a single 675 mg intramuscular injection in conjunction with a 30 mg dose of oral aripiprazole. The drug has a boxed warning for increased mortality in elderly patients with dementia-related psychosis and has several contraindications, including known hypersensitivity to aripiprazole. Common adverse reactions include akathisia, injection site pain, and increased weight. The drug is not approved for use in pediatric patients or for the treatment of patients with dementia-related psychosis.
Increased mortality in elderly patients with dementia-related psychosis
Avoid use in patients who are known CYP2D6 poor metabolizers or taking strong CYP3A4 inhibitors, strong CYP2D6 inhibitors, or strong CYP3A4 inducers
Single 675 mg intramuscular injection in conjunction with 30 mg oral aripiprazole
Not established
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