oxybutynin

Warning

Oxybutynin can cause serious side effects, including urinary retention, gastric retention, and uncontrolled narrow-angle glaucoma

Contraindications

• Urinary retention
• Gastric retention
• Uncontrolled narrow-angle glaucoma
• Known hypersensitivity to oxybutynin chloride or any component of oxybutynin chloride extended-release tablets

Adverse Reactions

• Dry mouth
• Constipation
• Diarrhea
• Headache
• Somnolence
• Dizziness

General Guidance

Dosage may be adjusted in 5 mg increments to achieve a balance of efficacy and tolerability, up to a maximum of 30 mg/day for adults and 20 mg/day for pediatric patients

Pregnancy

• There are no adequate data on oxybutynin chloride extended-release tablets use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes

Nursing Mothers

Pediatric Use

• Oxybutynin chloride extended-release tablets are not recommended in pediatric patients who cannot swallow the tablet whole without chewing, dividing, or crushing, or in children under the age of 6

Geriatric Use

• The rate and severity of anticholinergic effects reported by patients less than 65 years old and those 65 years and older were similar