escitalopram oxalate

Warning

Increased risk of suicidal thoughts and behaviors, serotonin syndrome, and discontinuation symptoms

Contraindications

• Use of MAOIs intended to treat psychiatric disorders
• Use of pimozide
• Known hypersensitivity to escitalopram or citalopram

Adverse Reactions

• Insomnia
• Ejaculation disorder
• Nausea
• Sweating increased
• Fatigue
• Somnolence

General Guidance

Dose adjustments may be necessary for elderly patients, patients with hepatic impairment, and patients with severe renal impairment

Pregnancy

• Use during pregnancy only if the potential benefit justifies the potential risk to the fetus
• Increased risk of persistent pulmonary hypertension of the newborn (PPHN)

Nursing Mothers

• Escitalopram is excreted in human breast milk
• Caution should be exercised when escitalopram is administered to a nursing woman

Pediatric Use

• Safety and effectiveness have been established in adolescents (12 to 17 years of age) for the treatment of MDD
• Safety and effectiveness have not been established in pediatric patients less than 12 years of age

Geriatric Use

• Approximately 6% of patients in clinical trials were 60 years of age or older
• Greater sensitivity to effects of escitalopram cannot be ruled out in elderly individuals