Diclofenac Sodium

DICLOFENAC

Manufacturer: Bryant Ranch Prepack

Score: 145.0

Quick Summary

Diclofenac sodium topical solution is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of signs and symptoms of osteoarthritis of the knee(s). The recommended dose is 40 drops per knee, 4 times a day. It has several safety considerations, including an increased risk of serious cardiovascular thrombotic events and gastrointestinal bleeding. The drug is contraindicated in patients with known hypersensitivity, asthma, urticaria, or other allergic-type reactions, and in the setting of coronary artery bypass graft (CABG) surgery.

Key Clinical Findings and Indications

Treatment of signs and symptoms of osteoarthritis of the knee(s)
Relief of pain and inflammation

Important Safety Information

Warning

Increased risk of serious cardiovascular thrombotic events and gastrointestinal bleeding

Contraindications

Known hypersensitivity to diclofenac or any components of the drug product
History of asthma, urticaria, or other allergic-type reactions
Setting of coronary artery bypass graft (CABG) surgery

Adverse Reactions

Application site skin reactions (dryness, erythema, induration, vesicles, paresthesia, pruritus, vasodilation, acne, urticaria)
Gastrointestinal events (nausea, dyspepsia, diarrhea, abdominal pain)
Cardiovascular events (palpitation, cardiovascular disorder)