ETODOLAC
Manufacturer: Aphena Pharma Solutions - Tennessee, LLC
Score: 144.0
Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used for the management of signs and symptoms of osteoarthritis, rheumatoid arthritis, and for the management of acute pain. It has anti-inflammatory, analgesic, and antipyretic activities. However, it is associated with serious cardiovascular and gastrointestinal risks, and its use should be carefully considered in patients with certain medical conditions. The recommended dose is 200-400 mg every 6-8 hours for acute pain, and 300-500 mg twice a day for osteoarthritis and rheumatoid arthritis. Special considerations are needed for use in pregnancy, nursing mothers, pediatric patients, and geriatric patients.
Cardiovascular thrombotic events, gastrointestinal bleeding, and renal impairment
Dose adjustment is generally not required in patients with mild to moderate renal impairment, but caution is advised in patients with severe renal impairment.
200-400 mg every 6-8 hours
Not established
300-500 mg twice a day
Not established