Meloxicam

MELOXICAM

Manufacturer: Lupin Pharmaceuticals, Inc.

Score: 141.0

Quick Summary

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. It works by reducing inflammation and pain in the body. Meloxicam is available in tablet form and should be taken with a full glass of water. The recommended dose is 7.5 mg once daily, which may be increased to 15 mg once daily if needed. Meloxicam has several potential side effects, including gastrointestinal problems, increased risk of heart attack and stroke, and liver damage. It is also contraindicated in patients with certain medical conditions, such as asthma, and those taking certain medications, such as warfarin. Special considerations should be taken when using meloxicam in pregnant or nursing women, pediatric patients, and geriatric patients.

Key Clinical Findings and Indications

Meloxicam is used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis
It reduces inflammation and pain in the body
The recommended dose is 7.5 mg once daily, which may be increased to 15 mg once daily if needed

Important Safety Information

Warning

Meloxicam may increase the risk of heart attack and stroke, and may cause gastrointestinal problems and liver damage

Contraindications

Patients with asthma
Patients with certain medical conditions, such as heart disease or liver disease
Patients taking certain medications, such as warfarin

Adverse Reactions

Gastrointestinal problems, such as nausea and diarrhea
Increased risk of heart attack and stroke
Liver damage

Dosing Recommendations

General Guidance

Dose adjustments may be necessary in patients with certain medical conditions, such as kidney or liver disease

Osteoarthritis

Adult Dose

7.5 mg once daily, which may be increased to 15 mg once daily if needed

Pediatric Dose

Not recommended for pediatric patients under 2 years of age

Rheumatoid arthritis

Adult Dose

7.5 mg once daily, which may be increased to 15 mg once daily if needed

Pediatric Dose

Not recommended for pediatric patients under 2 years of age

Special Population Considerations

Pregnancy

Meloxicam should be used with caution in pregnant women, as it may increase the risk of premature closure of the ductus arteriosus in the fetus

Nursing Mothers

Meloxicam is excreted in breast milk, and caution should be exercised when using it in nursing mothers

Pediatric Use

Meloxicam is not recommended for pediatric patients under 2 years of age
The safety and effectiveness of meloxicam in pediatric patients over 2 years of age has been evaluated in clinical trials

Geriatric Use

Meloxicam should be used with caution in geriatric patients, as they may be more sensitive to its effects

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