FLUOXETINE HCL
Manufacturer: Strides Pharma Science Limited
Score: 144.0
Fluoxetine HCl is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Bulimia Nervosa, and Panic Disorder. It works by increasing the levels of serotonin in the brain, helping to improve mood and reduce symptoms of these conditions. The drug has various adverse reactions, including suicidal thoughts and behaviors, serotonin syndrome, and allergic reactions, and has important safety information and contraindications, such as the risk of postpartum hemorrhage and the potential for interaction with other medications. Dosing recommendations vary depending on the condition being treated and the patient population, with initial dosing and titration details provided for adults and pediatric patients. Special population considerations include use during pregnancy, nursing mothers, pediatric use, and geriatric use.
Increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults
Use a lower or less frequent dosage in patients with hepatic impairment, the elderly, and for patients with concurrent disease or on multiple concomitant medications
20 mg/day in morning (initial dose), 20-80 mg/day (target dose)
10-20 mg/day (initial dose), 10-60 mg/day (target dose)
20 mg/day in morning (initial dose), 20-60 mg/day (target dose)
10 mg/day (initial dose), 10-60 mg/day (target dose)
60 mg/day in morning
Not established
10 mg/day (initial dose), 20-60 mg/day (target dose)
Not established