ACEBUTOLOL HYDROCHLORIDE
Manufacturer: Golden State Medical Supply, Inc.
Score: 141.0
Acebutolol Hydrochloride is a selective beta-adrenoreceptor blocking agent used for the management of hypertension and ventricular arrhythmias. It is available in capsule form for oral administration. The initial dosage for hypertension is 400 mg, which can be given as a single daily dose or in divided doses. For ventricular arrhythmia, the usual initial dose is 400 mg daily, given as 200 mg twice daily, with gradual increases until optimal clinical response is achieved. The drug has several contraindications, including persistently severe bradycardia, second- and third-degree heart block, overt cardiac failure, and cardiogenic shock. Important safety information includes warnings about cardiac failure, exacerbation of ischemic heart disease, and potential interactions with other medications. Special population considerations include use during pregnancy, nursing mothers, pediatric use, and geriatric use, with specific recommendations for dosing and monitoring.
Cardiac failure, exacerbation of ischemic heart disease, and potential interactions with other medications
Doses above 800 mg/day should be avoided in the elderly
400 mg daily, given as a single dose or in divided doses
Not established
400 mg daily, given as 200 mg twice daily, with gradual increases until optimal clinical response is achieved
Not established