NAPROXEN
Manufacturer: Camber Pharmaceuticals, Inc.
Score: 148.0
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendonitis, bursitis, acute gout, pain, and primary dysmenorrhea. It works by inhibiting the production of prostaglandins, which cause pain and inflammation. The recommended dose varies depending on the condition being treated, and it is essential to use the lowest effective dose for the shortest duration possible to minimize the risk of adverse reactions. Naproxen is contraindicated in patients with known hypersensitivity to the drug, asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs, and in the setting of coronary artery bypass graft (CABG) surgery. Special considerations are necessary for use in pregnancy, nursing mothers, pediatric patients, and geriatric patients due to potential risks and side effects.
Increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, and gastrointestinal bleeding, ulceration, and perforation.
Use the lowest effective dose for the shortest duration possible to minimize the risk of adverse reactions.
250 mg (10 mL) or 375 mg (15 mL) or 500 mg (20 mL) twice daily
Not established for patients under 2 years of age; for patients 2 years and older, 5 mg/kg/day given in 2 divided doses
Not applicable
10 mg/kg/day given in 2 divided doses
500 mg (20 mL) initially, followed by 250 mg (10 mL) every 6 to 8 hours as required
Not established
750 mg (30 mL) initially, followed by 250 mg (10 mL) every 8 hours until the attack has subsided
Not established