OMEPRAZOLE, SODIUM BICARBONATE
Manufacturer: Bryant Ranch Prepack
Score: 141.0
Omeprazole and Sodium Bicarbonate capsules are a proton pump inhibitor (PPI) indicated for the short-term treatment of active duodenal ulcer, active benign gastric ulcer, treatment of heartburn and other symptoms associated with GERD, and the treatment of erosive esophagitis (EE) due to acid-mediated GERD. The capsules contain 20 mg or 40 mg of omeprazole and 1100 mg of sodium bicarbonate. The recommended dosage regimen is based on the indication and ranges from 20 mg to 40 mg once daily. Important safety information includes contraindications such as known hypersensitivity to substituted benzimidazoles or any components of the formulation, and patients receiving rilpivirine-containing products. Adverse reactions include headache, abdominal pain, nausea, diarrhea, vomiting, and flatulence. Special population considerations include use in pregnancy, pediatric use, geriatric use, and patients with renal or hepatic impairment.
Acute tubulointerstitial nephritis, Clostridium difficile-associated diarrhea, bone fracture, cutaneous and systemic lupus erythematosus, cyanocobalamin (vitamin B-12) deficiency, hypomagnesemia, and fundic gland polyps.
No dosage adjustment is necessary in the elderly.
20 mg once daily for 4 weeks
Not established
40 mg once daily for 4 to 8 weeks
Not established
20 mg once daily for up to 4 weeks
Not established
20 mg once daily for 4 to 8 weeks
Not established