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Morphine Sulfate

MORPHINE SULFATE

Manufacturer: Bryant Ranch Prepack

Score: 144.0

Quick Summary

Morphine sulfate is an opioid analgesic indicated for the relief of moderate to severe acute and chronic pain. It is available in various concentrations and formulations, including oral solutions. The drug has several potential side effects, including respiratory depression, constipation, and nausea. Morphine sulfate is contraindicated in patients with known hypersensitivity, respiratory depression, acute or severe bronchial asthma, and paralytic ileus. The initial dosing and titration of morphine sulfate depend on the patient's condition, age, and medical history. Special population considerations include use during pregnancy, nursing mothers, pediatric use, and geriatric use.

Key Clinical Findings and Indications

  • Relief of moderate to severe acute and chronic pain
  • Opioid agonist
  • Available in various concentrations and formulations
  • Indicated for opioid-tolerant patients

Important Safety Information

Warning

Risk of medication errors, respiratory depression, and overdose

Contraindications

  • Known hypersensitivity to morphine
  • Respiratory depression
  • Acute or severe bronchial asthma
  • Paralytic ileus

Adverse Reactions

  • Respiratory depression
  • Constipation
  • Nausea
  • Sedation
  • Dizziness

Dosing Recommendations

General Guidance

Titrate dose based on individual patient response

Moderate to severe pain

Adult Dose

10-20 mg every 4 hours as needed

Pediatric Dose

Not established

Special Population Considerations

Pregnancy

  • Use only if clearly needed
  • Potential risk of fetal harm
  • Monitor for neonatal withdrawal symptoms

Nursing Mothers

  • Low levels of morphine sulfate in breast milk
  • Monitor infant for respiratory depression and sedation

Pediatric Use

  • Safety and effectiveness not established
  • Use with caution

Geriatric Use

  • Increased sensitivity to morphine sulfate
  • Use with caution
  • Monitor for respiratory depression and sedation