TIZANIDNE HYDROCHLORIDE
Manufacturer: Bryant Ranch Prepack
Score: 142.0
Tizanidine hydrochloride is a central alpha-2-adrenergic agonist used for the management of spasticity. It is available in 6 mg capsules and should be taken with or without food, with a recommended starting dose of 2 mg and a maximum daily dose of 36 mg. The drug has several important safety considerations, including contraindications with potent CYP1A2 inhibitors, warnings for hypotension, liver injury, sedation, hallucinosis, and hypersensitivity reactions. Dose adjustments are necessary for patients with renal or hepatic impairment, and special considerations are needed for use in pregnancy, nursing mothers, pediatric, and geriatric populations.
Contraindicated with potent CYP1A2 inhibitors, warnings for hypotension, liver injury, sedation, hallucinosis, and hypersensitivity reactions
Dose adjustments necessary for patients with renal or hepatic impairment
2 mg, repeated at 6- to 8-hour intervals, up to a maximum of 3 doses in 24 hours
Not established