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MLK F4 Kit

TRIAMCINOLONE ACETONIDE, LIDOCAINE HYDROCHLORIDE, BUPIVACAINE HYDROCHLORIDE, POVIDINE IODINE

Manufacturer: Asclemed USA, Inc.

Score: 146.0

Quick Summary

The MLK F4 Kit is used for various medical procedures, including local or regional anesthesia, analgesia, and skin preparation. It contains a combination of triamcinolone acetonide, lidocaine hydrochloride, bupivacaine hydrochloride, and povidine iodine. The kit is indicated for production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. However, it is contraindicated for obstetrical paracervical block anesthesia and intravenous regional anesthesia. The recommended concentrations and dosages vary depending on the type of block and procedure being performed.

Key Clinical Findings and Indications

  • Local or regional anesthesia
  • Analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures
  • Obstetrical procedures
  • Intra-articular injections for conditions such as rheumatoid arthritis and osteoarthritis
  • Intramuscular injections for conditions such as allergic reactions and dermatologic diseases

Important Safety Information

Warning

Risk of cardiac arrest with use of bupivacaine hydrochloride in obstetrical anesthesia

Contraindications

  • Obstetrical paracervical block anesthesia
  • Intravenous regional anesthesia
  • Hypersensitivity to any of the components

Adverse Reactions

  • Cardiovascular toxicity
  • Central nervous system toxicity
  • Allergic reactions
  • Methemoglobinemia

Dosing Recommendations

General Guidance

Dose adjustments should be made based on the patient's response and the presence of any adverse reactions

Local infiltration

Adult Dose

0.25% to 0.5% solution, 1 to 60 mL (2.5 to 300 mg)

Pediatric Dose

Not recommended for pediatric patients younger than 12 years

Epidural block

Adult Dose

0.5% to 0.75% solution, 10 to 20 mL (50 to 150 mg)

Pediatric Dose

Not recommended for pediatric patients younger than 12 years

Special Population Considerations

Pregnancy

  • Bupivacaine hydrochloride is contraindicated for obstetrical paracervical block anesthesia
  • Use with caution in pregnant women, as it may cause fetal bradycardia and death

Nursing Mothers

  • Caution should be exercised when administering the drug to nursing mothers, as it may be excreted in human milk

Pediatric Use

  • Not recommended for pediatric patients younger than 12 years
  • Use with caution in pediatric patients, as it may cause cardiovascular toxicity and central nervous system toxicity

Geriatric Use

  • Use with caution in geriatric patients, as they may be more susceptible to the toxic effects of the drug
  • Dose adjustments may be necessary in geriatric patients

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