Verzenio

Warning

Diarrhea, neutropenia, and hepatotoxicity

Contraindications

• None

Adverse Reactions

• Diarrhea
• Neutropenia
• Nausea
• Abdominal pain
• Infections
• Fatigue
• Anemia
• Leukopenia
• Decreased appetite
• Vomiting
• Headache
• Alopecia
• Thrombocytopenia

General Guidance

Dose modifications may be necessary for adverse reactions, with dose reductions to 100 mg twice daily or 50 mg twice daily as needed.

Pregnancy

• Based on findings in animals and its mechanism of action, Verzenio can cause fetal harm when administered to a pregnant woman.

Nursing Mothers

• No information available

Pediatric Use

• The safety and effectiveness of Verzenio have not been established in pediatric patients.

Geriatric Use

• No overall differences in safety or effectiveness of Verzenio were observed between patients ≥65 years of age and younger patients.